Pubblications

Lavori scientifici e pubblicazioni / Clinical studies and pubblications

FREE ASPIRE

The kalos device: experimental protocol for airway clearance in patients with ineffective cough
Stefano Belli1 , F. Masocco1 , Davide Cattaneo1 , G. Savio1 ,B.Balbi1.
1 ICS Maugeri, Istituto Scientifico di Veruno (Veruno, IT)
5th ERCA Lione 2018

A pilot study on the non-invasive management of tracheobronchial secretions in tracheotomised patients
Stefano Belli1 , Davide Cattaneo1 , F. D’Abrosca2 , I. Prince1 , G. Savio1 ,B.Balbi1 .
1 ICS Maugeri, Istituto Scientifico di Veruno (Veruno, IT) 2 IRCCS Ca’ Granda-Ospedale Maggiore Policlinico (Milano, IT)
5th ERCA Lione 2018

Management of the airway in the tracheostomy patient in critical areas: a comparison of two devices for a pilot study.
L.Cavanna1 PT, C. Blardone2 PT, M. Bertoni MD3 , P. Severgnini MD4
1/3 Rehabilitation Department ASST-Sette Laghi, Varese; 2 Pulmonology Department ASST-Sette Laghi, Varese; 4 University of Insubria – DBSV – ICU ASST Settelaghi Varese, Italy;
5th ERCA Lione 2018

Running title: EFA and pep physiotherapy after pulmonary lobectomy
Nicola Rotolo1 , Maria Cattoni1 , Michele D’Andria1 , Laura Cavanna1 , Giorgia Patrizio1 , Cecilia Sampietro1 , Lorenzo Dominioni1 , Annamaria Grande1 , Andrea Imperatori1 , Erminia d’Amanzio1 , Antonello Nicolini2
1 Center for Thoracic Surgery, University of Insubria, Ospedale di Circolo, Varese, Italy 2 Respiratory Diseases Unit,Hospital of Sestri Levante,Italy
5th ERCA Lione 2018

Consecutive use of flow accelerator and cough assistant in patients with neuro-muscular pathology: 2 clinical cases
Mantellini E., MD, Pizzorno M.,
PT Respiratory Rehabilitation Alessandria Hospital Italy
5th ERCA Lione 2018

Synergic action between expiratory flow accelerator (free aspire) and the in-exsufflator in secretions removal of patient complex: case report
Giancarlo Garuti MD Respiratory Diseses Dpt;
Santa Maria Bianca Hospital, Mirandola ; Local Health Unit, Modena, Italy
5th ERCA Lione 2018

UNIKO TPEP

European Respiratory Society guidelines for the management of adult bronchiectasis
Eva Polverino1, Pieter C. Goeminne2 , 3, Melissa J. McDonnell4, 5, 6, Stefano Aliberti7, Sara E. Marshall8, Michael R. Loebinger9, Marlene Murris10, Rafael Cantón11, Antoni Torres12, Katerina Dimakou13, Anthony De Soyza4, 15, Adam T. Hill16, Charles S. Haworth17, Montserrat Vendrell18, Felix C. Ringshausen19, Dragan Subotic20, Robert Wilson9, Jordi Vilaró21, Bjorn Stallberg22, Tobias Welte19, Gernot Rohde23, Francesco Blasi7, Stuart Elborn9, 24, Marta Almagro25, Alan Timothy25, Thomas Ruddy25, Thomy Tonia26, David Rigau27 and James D. Chalmers28
Eur Respir J 2017; 50: 1700629

Comparison of effectiveness of temporary positive expirayory pressure versus oscillatory positive expiratory pressure in severe COPD patients
A. Nicolini1, V. Mascardi1, B. Grechi2, M- Ferrari-Bravo3, P.Banfi4, C. Barlascini5
1Respiratory Diseases Unit, Hospital of Sestri Levante, Italy, 2Physical Medicine and Rehabilitation, ASL 4 Chiavarese, Italy, 3Statistics and Biometrics Unit, ASL 4 Chiavarese, Italy, 4Don Gnocchi Foundation, IRCSS, Milan, Italy, 5Hygiene and Health Medicine, ASL4 Chiavarese, Italy

Clin Respir J. 2017;1–9

FREE ASPIRE

Free aspire: a new device for the management of airways clearance in patient with ineffective cough
Luca Bertelli1, Giovanni Di Nardo2, Salvatore Cazzato3, Giampaolo Ricci1, Andrea Pession1
1Department of Pediatrics, University of Bologna, S. Orsola-Malpighi Hospital; 2Pediatric Gastroenterology Unit, AORN Santobono-Pausilipon, Naples; 3Department of Mother and Child Health, Salesi Children’s Hospital, Ancona, Italy
Pediatric Reports 2017; volume 9:7270

L’efficacia della tecnica “vacuum” nella riduzione delle riacutizzazioni bronchiali nei pazienti con malattia di Parkinson con deficit della deglutizione
D. Terzaghi1, P.Latorre2,G. Riboldazzi2
1Fisioterapista Libero Professionista 2ORL- Foniatra Università dell’Insubria – Varese 2Neurologo Parkinsonologo- Università dell’Insubria – Varese
XXXVI SIAF 2017 Siena

Evaluation of tolerability, ease of use, perception of mucus encumbrance of an alternative device (FreeAspire ®) for management secretions in patients with bulbar Amyotrophic Lateral Sclerosis
A. Mattei1, E. Rindone1, S. Marchisio1, M. Bellocchia1, R. Ambrosanio1, G. Tabbia1, E. Clivati1, M. Bardessono1, C. Bucca1
1AOU Città della salute e della Scienza Presidio MOLINETTE SC Pneumologia U – Turin (Italy)
ERS 2017 Milan

Gestione non invasiva delle secrezioni bronchiali in pazienti tracheostomizzati
Stefano Belli1, Davide Cattaneo1, Ilaria Prince1, Francesco D’abrosca2, Savio Gloria1, Claudia Carai3, Bruno Balbi1
1Pneumologia Riabilitativa, ICS Maugeri – istituto scientifico di Veruno – Veruno (NO) 2Riabilitazione, Fondazione IRCCS Ca’ Granda – Ospedale Maggiore Policlinico – Milano 3Riabilitazione, Casa di cura Villa Esperia – Salice Terme
AIPO 2017 Bologna

UNIKO TPEP

Comparing airways clearance techniques in chronic obstructive pulmonary disease and bronchiectasis: positive expiratory pressure or temporary positive expiratory pressure? A retrospective study
Francesco D’Abroscaa,b,∗, Barbara Garabellia,c, Gloria Savioa, Agnese Barisona, Lorenzo Appendinia, Luis V.F. Oliveirad, Paola Baiardie, Bruno Balbia
a
Divisione di Pneumologia Riabilitativa, Fondazione Salvatore Maugeri, I.R.C.C.S., Centro Medico di Veruno, Veruno, NO, Italy. bFondazione IRCCS Ca’ Granda — Ospedale Maggiore Policlinico Milano, Milano, MI, Italy
cNEMO Center — Centro Clinico NEMO, Ospedale Niguarda Cà Granda, Milano, Milano, MI, Italy
dPrograma de Pós-Graduac¸ão em Ciências da Reabilitac¸ão, Universidade Nove de Julho (UNINOVE), São Paulo, SP, Brazil
eDirezione Scientifica Centrale, Fondazione Salvatore Maugeri, I.R.C.C.S., Pavia, PV, Italy
Braz J Phys Ther. (2017), http://dx.doi.org/10.1016/j.bjpt.2016.12.001

Effectiveness of temporary positive expiratory pressure (T-PEP) at home and at hospital in patients with severe chronic obstructive pulmonary disease
Valentina Mascardi1, Bruna Grecchi2, Cornelius Barlascini3, Paolo Banfi4, Antonello Nicolini1
1
Respiratory Diseases Unit, Hospital of Sestri Levante, Sestri Levante, Italy; 2Physical Medicine and Rehabilitation, Chiavari, Italy; 3Hygiene and Health Medicine Hospital of Sestri Levante, Sestri Levante, Italy; 4Pulmonary Diseases Unit, Don Gnocchi Foundation IRCCS, Milan, Italy
Journal of Thoracic Disease 2016;8(10):2895-2902

L’efficacia della TPEP nella gestione dell’emottisi
Lo Piparo, A. Ferlisi, F Ficili, M.A. Orlando, L Termini, G. Traverso, S. Barrale, M.R. Bonaccorso, M. Collura
U.O. Pediatria II per la FIBROSI CISTICA (CRR) e le Malattie Respiratorie – Allergologia – Ospedale dei Bambini “G. Di Cristina” Palermo
SIFC Salerno 2016

Effectiveness of Temporary Positive Expiratory Pressure (T-PEP) at Home and at Hospital in PatientsWith Severe COPD
Ines Piroddi MD Antonello Nicolini MD*; and Giovanni Veronesi MD Respiratory Diseases Unit, Sestri Levante, Italy
Chest.
2016; 149(4_S):A490-A490. doi: 10.1016/j.chest.2016.02.511

Comparison of Effectiveness of Two Positive Expiratory Pressure Devices In Severe COPD Patients:
Temporary Positive Expirayory Pressure (T-PEP) Versus Oscillatory Positive Expiratory Pressure (O-PEP)
Antonello Nicolini MD* Respiratory Diseases Unit, Sestri Levante, Italy
Chest.
2016; 149(4_S):A364-A364. doi: 10.1016/j.chest.2016.02.379

Short-term effects of three slow expiratory airway clearance techniques in patients with bronchiectasis: a randomised crossover trial.
Herrero-Cortina B1, Vilaró J2, Martí D3, Torres A4, San Miguel-Pagola M5, Alcaraz V3, Polverino E3.
1
Pneumology Department, Clinic Institute of Thorax, Hospital Clinic of Barcelona, Institut d́Investigacions Biomèdiques August Pi I Sunyer – Centro de Investigación Biomédica En Red-Enfermedades Respiratorias, Barcelona, Spain; Health Sciences Faculty, San Jorge University, Zaragoza, Spain.
2Health Sciences Faculty Blanquerna, Physiotherapy Research Group, Ramon Llull University, Barcelona, Spain.
3Pneumology Department, Clinic Institute of Thorax, Hospital Clinic of Barcelona, Institut d́Investigacions Biomèdiques August Pi I Sunyer – Centro de Investigación Biomédica En Red-Enfermedades Respiratorias, Barcelona, Spain.
4Pneumology Department, Clinic Institute of Thorax, Hospital Clinic of Barcelona, Institut d́Investigacions Biomèdiques August Pi I Sunyer – Centro de Investigación Biomédica En Red-Enfermedades Respiratorias, Barcelona, Spain; University of Barcelona, Barcelona, Spain. Electronic address:
atorres@clinic.ub.es.
5Health Sciences Faculty, San Jorge University, Zaragoza, Spain.

Physiotherapy. 2015 Dec 1. pii: S0031-9406(15)03852-3. doi: 10.1016/j.physio.2015.07.

FREE ASPIRE

Efficacia della tecnica vacuum nella riduzione delle riacutizzazioni bronchiali in soggetti Parkinson con deficit della deglutizione: studio pilota.
Tesi di Laurea di: Dario Terzaghi
Università degli studi dell’Insubria – Corso di Laurea in Fisioterapia – Varese 2015/2016

Management of bronchial secretions with Free Aspire in children with cerebral palsy: impact on clinical outcomes and healthcare resources
Giancarlo Garuti1*, Elisa Verucchi2 , Isabella Fanelli3 , Michele Giovannini1 , Joao Carlos Winck4 and Mirco Lusuardi5
1Pneumology Unit, Santa Maria Bianca Hospital, via Fogazzaro 1, Mirandola (MO), 41025 Modena, Italy. 2Italian Union against Muscular Dystrophy (UILDM), Modena and Reggio Emilia Sections, Modena, Italy. 3public Health Care Department, Child Neuropsychiatric Unit, Modena, Italy. 4Faculdade de Medicina, Universidade do Porto, Porto, Portugal. 5Respiratory Rehabilitation Unit, S. Sebastiano Hospital, Correggio (RE), and UILDM, Reggio Emilia, Italy.
Italian Journal of Pediatrics (2016) 42:7

UNIKO TPEP

Effectiveness of Temporary Positive Expiratory Pressure (TPEP) at home and at Hospital in patients with severe COPD
Valentina Mascardi1, Ines Maria Grazia Piroddi1, Bruna Grechi2, Antonello Nicolini1
1Respiratory Diseases, Respiratory Rehabilitation Unit, Sestri Levante, Italy; 2Rehabilitation Medicine, Physical Medicine and Rehabilitation, sestri Levante, Italy
ERS Amsterdam 2015

Comparison of effectiveness of two positive expiratory devices in severe COPD patients: Temporary positive expiratory pressure (TPEP) versus oscillatory positive expiratory presure (OPEP)
Antonello Nicolini1, Valentina Mascardi1, Bruna Grechi2
1Respiratory Diseases, Respiratory Rehabilitation Unit, Sestri Levante, Italy; 2Rehabilitation Medicine, Physical Medicine and Rehabilitation, sestri Levante, Italy
ERS Amsterdam 2015

Effectiveness of Temporary Positive Expiratory Pressure (TPEP) at home and at Hospital in patients with severe COPD
Nicolini Antonello, Perazzo Alssandro, Colamartino Simona, Gatto Piergiorgio, Piroddi Maria Grazia, grechi Bruna
Respiratory Rehabilitation Unit, General Hospital of sestri Levante, Italy
ERCA-JVD Lyon March 2015

Could Temporary Positive Expiratory Presure (TPEP) be useful as respiratory physiotherapy technique for patient affected by non-CF bronchiectasis?
Bruno Iovine MD, Emanuele Giovanni Conte MD, Marco Scapigliati RRT, Roberta Marra MD, Riccardo Inchingolo MD, Mariangela Retucci RRT, Silvia Giannone RRT, Mariapia Torrice RRT, Salvatore Valente MD, Andrea Smargiassi MD
Pulmonary Medicine Department, University Hospital A. Gemelli, Rome Italy
ERCA-JVD Lyon March 2015

Wet sputum as an objective outcome in a randomized crossover trial in non CF-BE: reliability and responsiveness
Herrero B1, Vilarò J2, SanMiguel M1, Alcaraz V3, Torres A3, Polverino E31Health Sciences Faculty, San Jorge University, Zaragoza, Spain
2
Health Sciences Faculty Blanquerna, Physiotherapy Research Group (GreFis), Ramon Llull University, Barcelona, Spain
3
Pneumology Department, clinic Institute of Thorax (ICT), Hospital Clinic of Barcelona, Institut d’investigaciones Biomèdiques August Pi I Sunyer (IDIBAPS)- Centro de investigaciòn Biomèdica En Red-Enfermedades Respiratorias (CIBERES CB06/06/0028), Spain
ERCA-JVD Lyon March 2015

FREE ASPIRE

Efficacia del sistema vaküm in pazienti adulti affetti da patologie respiratorie croniche ostruttive ed ipersecrezione bronchiale.
Tesi di Laurea di: Matteo Gubertini
Università degli studi mi Modena e Reggio Emilia – corso di Laurea in Fisioterapia – Modena 2014/2015

Tracheostomized (TCS) patients: Is it possible to manage noninvasively tracheobronchial secretions?
Francesco D’Abrosca1, Ilaria Prince1, stefano Belli1, Claudia Carai1, Michela Moroso1, Davide Vallese1, Elisa Spada1, Sergio Zaccaria1, Bruno Balbi1
1Pulmonary Rehabilitation, Fondazione Salvatore Maugeri, I.R.C.C.S., Veruno, Novara, Italy
ERS Amsterdam 2015

Efficacia ed accettabilità del trattamento disostruttivo delle vie aeree con tecnologia Vaküm in soggetti con tosse ipovalida
G. Bardasi
71° Congresso Italiano di Pediatria vincitore premio comunicazione orale
Pediatria numero 7-8 luglio – agosto 2015

The role of the FREE ASPIRE in the management of the secretions in patients affected by cerebral palsy and its impact in use of health care resources
Garuti*, M Lusuardi*, B. Turola*, E. Verucchi**, M. Giovannini
Santa Maria Bianca Hospital, Mirandola (MO), Local Health Authority of Modena
*San Sebastiano Hospital, Correggio (RE), Local Health Authority of Reggio Emilia
**Italian Union Against Muscolar Distrophy, Modena Section, Italy
ERCA-JVD Lyon March 2015

Noninvasive management of tracheobronchial secretions in tracheostomized (TCS) patients
D’Abrosca F, Belli S, Carai C, Moroso M, Pince I, Vallese D, Balbi B
Divisione di Pneumologia Riabilitativa, Fondazione S. Maugeri, IRCCS, Veruno (NO), Italy
ERCA-JVD Lyon March 2015

Efficacy of Vaküm technology in patients with chronic hypersecretion: a multicentre randomised clinical trial
1,2Venturelli E, 2Tonelli R, 1Righi D, 1Furino V, 3Cavicchioli P, 4Galimberti V, 5Albero A, 6Colaioli A, 7Saleri M, 8Castellani C, 3Vagheggini G, 4Zaurino M,
4Schiavoni PG, 7Bianchi L, 7Vitacca M, 5Palumbo L, 5Colombo F, 6Pasqua F, 6Cardaci V, 8Gigliotti F, 3Ambrosino N, 1,2Clini E
1
Villa Pineta Hospital, Lung Unit and pulmonary Rehabilitation and 2University of Modena and Reggio Emilia, 3Rehabilitation Centre Auxilium Vitae- Volterra (Pisa), 4Pulmonary Rehabilitation Unit of San Giuseppe Multimedica Hospital. Milan, 5Dpt. Of Rehabilitative Pneumology- Cuasso al Monte (Varese), 6San Raffaele IRCCS- Rome, 7Maugeri Foundation IRCCS-Lumezzane (Brescia), 8Rehabilitation Centredon Gnocchi IRCCS- Florence
ERCA-JVD Lyon March 2015

FREE ASPIRE versus PEP bottle in the tracheobronchial secretion removal in patients undergoing pulmonary lebectomy: a preliminary prospective and randomized study on 50 patients
D’Andria1, E. D?amanzio1, L. Cavanna2, G. Patrizio3, M. Cattoni4, C. Sampietro4, A. Imperatori4, L. Dominioni4, N. Rotolo4
1
Degree course in Physiotherapy, School of Medicine, University of Insubria, Varese, Italy
2
Neuromotor Rheabilitation Unit, Ospedale di Circolo, Varese, Italy
3
Pneumology Unit, Ospedale di Circolo, Varese, Italy
4
Center of Thoracic Surgery, University of Insubria, Ospedale di Circolo , Varese, Italy
ERCA-JVD Lyon March 2015

UNIKO

Comparison of intermittent positive pressure breathing and temporary positive expiratory pressure in patients with severe chronic obstructive pulmonary disease.
Nicolini A, Mollar E, Grecchi B, Landucci N.
Arch Bronconeumol. 2014 Jan;50(1):18-24. doi: 10.1016/j.arbres.2013.07.019. Epub 2013 Dec 8. English, Spanish.

UNIKO

L’APPLICAZIONE DELLA TECNOLOGIA T-PEP NEL TRATTAMENTO FISIOKINESITERAPICO DEL PAZIENTE AFFETTO DA BRONCHIECTASIE: QUALI EFFETTI SULLA FUNZIONALITÀ RESPIRATORIA?
Tesi di Laurea di: Mariangela Retucci
UNIVERSITÀ CATTOLICA DEL SACRO CUORE – Corso di Laurea in Fisioterapia Roma 2013

LA FISIOKINESITERAPIA NEL PAZIENTE AFFETTO DA BRONCHIECTASIE: EFFETTI SULLA QUALITÀ DELLA VITA, SULLA CAPACITÀ D’ESERCIZIO FISICO E SULLA RIDUZIONE DELLA CARICA MICROBICA NELL’ESCREATO
Tesi di Laurea di: Silvia M. Giannone
UNIVERSITÀ CATTOLICA DEL SACRO CUORE – Corso di Laurea in Fisioterapia Roma 2013
Comparison of intermittent positive pressure breathing (IPPB) and temporary positive expiratory pressure (TPEP) in patients with severe chronic obstructive pulmonary disease
A. Nicolini, B. Grecchi, F. D’Abrosca (Sestri Levante, Veruno, Italy)
ERS 2013 Barcelona

Efficacy of temporary positive expiratory pressure (TPEP) in patients with chronic mucus hypersecretion. THE UNIKO PROJECT: a multicentre randomised trial.
Elena Venturelli1, Ernesto Crisafulli2, Assunta DeBiase2, Daniela Righi2, Daniele Berrighi3, Pier Paolo Cavicchioli3, Guido Vagheggini3, Francesco Dabrosca4, Bruno Balbi4, Mara Paneroni5, Luca Bianchi5, Michele Vitacca5, Vittoria Galimberti6, Michele Zaurino6, Giorgio Schiavoni6, Andrea Iattoni1, Nicolino Ambrosino3 and Enrico M Clini1,2
Clinical Rehabilitation April 2013;27(4) 336–346

One year experiencein intensive post-operative rehabilitation (cod.56) in adult after cardiac surgery
A. Frijia, F. Filippi, A. Gavarini, S. Balloni, M. Ceccarani, I. Luschi, S. Lazzarotti, M. Viscariello, P. Rossi, M. Petrilli Massa, Italy
2nd International conference on Respiratory Physiotherapy March 2013 Genova

Comparison of intermittent positive pressure breathing (IPPB) and temporary positive expiratory pressure (TPEP) in patients with severe chronic obstructive pulmonary disease
Elena Mollar, Antonello Nicolini, Pellegrina Lina Moretti,Norma Landucci, Paola Prato, Domenico Cianci Sestri Levante, GE, Italy Cornelius Barlascini, Maura Ferrari-Bravo Chiavari, GE, Italy
2nd International conference on Respiratory Physiotherapy – Oral presentation – March 2013 Genova

FREE ASPIRE

Effetti del sistema FREE ASPIRE nella disostruzione delle vie aeree. Studio su 50 pazienti sottoposti ad intervento di lobectomia polmonare.
Tesi di Laurea di: Michele D’Andria
Università degli studi dell’Insubria – Corso di Laurea in Fisioterapia – Varese 2012/2013

La gestione non invasiva delle secrezioni bronchiali in pazienti tracheotomizzati
Tesi di Laurea di: Claudia Carai
Universita’ degli studi del Piemonte Orientale “Amedeo Avogadro” Corso di laurea in Fisioterapia – Novara 2013

FREE-ASPIRE® and chest physioterapy in bronchial hypersecretion
Cavicchioli P, Vagheggini G, Panait E, Montagnani G, Berrighi D, Ambrosino N.
Pulmonary Rehabilitation Unit – Auxilium Vitae Rehabilitation Center, Volterra, Italy.
UIP 2013 Verona Italy

A non-invasive alternative to suction in tracheostomized (TCS) patients
D’Abrosca F, Moroso M, Carai C, Balbi B
Divisione di Pneumologia Riabilitativa, Fondazione S.Maugeri IRCCS – Veruno (NO, Italy)
UIP 2013 Verona Italy

One year experience in intensive post-operative rehabilitation (cod.56) in adult after cardiac surgery
A. Frijia, F. Filippi, A. Gavarini, S. Balloni, M. Ceccarani, I. Luschi, S. Lazzarotti, M. Viscariello, P. Rossi, M. Petrilli Massa, Italy
2nd International conference on Respiratory Physiotherapy March 2013 Genova

Free Aspire, an our experience
A. Bogetti, R. Cara, C. Colliva, Lonati, P. Pisano Genova, Italy
2nd International conference on Respiratory Physiotherapy March 2013 Genova

Eficacy of  VAKÜM Technology in chronic hypersecretion: a randomised clinical trial
Elena Venturelli, Pavullo nel Frignano, MO, Italy Pierpaolo Cavicchioli, Volterra, PI, Italy
Vittoria Galimberti, Milano, Italy Alessandro Gatta, Borsalino, AL, Italy Antonella Albero, Cuasso al Monte, VA, Italy Alessio Colaioli, Roma, Italy Manuela Saleri, Lumezzane, BS, ItalyCarla Castellani, Firenze, Italy
2nd International conference on Respiratory Physiotherapy – Oral presentation – March 2013 Genova

UNIKO

Airways Clearance Techniques inCystic Fibrosis: Physiology, Devices and the Future
Adrian H. Kendrick – Department of Respiratory Medicine, University Hospitals, Bristol
Cystic Fibrosis – Renewed Hopes Through Research – Edited by Dinesh Sriramulu 2012 |cap 22| 493-518

Efficacy of temporary positive expiratory pressure (TPEP) in patients with chronic mucus hypersecretion. THE UNIKO PROJECT: a multicentre randomised trial.
Venturelli E1, De Biase A.1, Paneroni M.1, Galimberti V.3,Cavicchioli P.4, D’Abrosca F.5
1Ospedale Villa Pineta and University of Modena – Pavullo n/F (MO); 2Fondazione Maugeri IRCCS – Lumezzane (BS); 3Ospedale San Giuseppe – Milano; 4Auxilium Vitae Rehabilitation Centre – Volterra (PI); 5Fondazione Maugeri IRCCS – Centre of Veruno (NO). Italy
4th ERCA – Barcellona – 2012

PEP-Mask and T-PEP: 4 years experience in a large cohort of hypersecretive patients.
D’Abrosca F1, Garabelli B1, Appendini L1, Savio G1 , Barison A1, Buschini N1, Baiardi P2, Balbi B1.
1Divisione di Pneumologia Riabilitativa, IRCCS Fondazione Salvatore Maugeri, Veruno, Novara,
Italy; 2Department of Statistics, Consorzio Valutazioni Biologiche Farmacologiche, Pavia, Italy.
4th ERCA – Barcellona – 2012

FREE ASPIRE

Disobstruction of the airways with Vaküm technology: pilot Study on the efficiency of the Free Aspire system with Torax Surgery patients.
Thesis by: Andrea Millefanti
Uuniversità degli studi dell’Insubria – Degree in Physiotherapy – Varese 2011/2012

The effects of the device Free-Aspire in patients with mildly impaired cough effectiveness.
Authors: 1Pierpaolo Cavichioli, 1Guido Vagheggini, 2Maria Ribeiro da Cunha, 1Nicolino Abrosino
1Weaning and Respiratory Rehabilitation Center of Auxilium Vitae, Volterra, Italy – 2Centro de Medicina de Reabilitaçao da Regiao Centro – Rovisco Pais, Portugal
9th Mediterranean Congress of PRM – Oral presentation – Sorrento, October 2012

Airways Clearance Techniques in Cystic Fibrosis: Physiology, Devices and the Future
Adrian H. Kendrick
Department of Respiratory Medicine, University Hospitals, Bristol
Cystic Fibrosis – Renewed Hopes Through Research – Edited by Dinesh Sriramulu 2012 |cap 22| 493-518

A non-invasive alternative to suction in tracheostomized (TCS) patients. 
D’Abrosca F, Ghizzi S, Balbi B.
Divisione di Pneumologia Riabilitativa, IRCCS Fondazione Salvatore Maugeri, Veruno, Novara, Italy.
4th ERCA – Barcelona- 2012

Disobstruction of the proximal airways with Vaküm technology: Study on the efficiency of the Free Aspire system with stage
III/IV COPD patients.
Bani Alunno C., D’amanzio E., Cabiaglia A., Palumbo L.
Hospital Firm “Ospedale di Circolo” Varese. Italy.
4th ERCA – Barcelona- 2012

FREE-ASPIRE and chest physiotherapy in bronchial hypersecretion
Cavicchioli P, Vagheggini G, Panailt E, Mazzoleni S, Montagnani G, reitano S, Ambrosino N.
Pulmonary Rehabilitation Unit – Auxilium Vitae Rehabilitation Centre, Volterra (PI), The BioRobotics Institute – Scuola
Superiore Sant’Anna, Pontedera, Italy.
4th ERCA – Oral presentation -Barcelona- 2012

Treatment of patients with ineffective cough: observational study about the use of the expiratory flow acceleartor FREE 
ASPIRE
1Pedroni A, 2Andreoli A, 2Cortelezzi A.
1Graduatating in physiotherapy, 2Luigi Sacco Hospital employees. Milano. Italy.
4th ERCA – Barcelona- 2012

UNIKO

Studio retrospettivo sulle metodiche di rimozione delle secrezioni tracho-bronchiali (Airway Clearance tecniques, ACT)
Autori: Francesco D’Abrosca1, Barbara Garabelli1, Lorenzo Appendini1, Gloria Savio1 ,Agnese Barison1, Nadia Buschini1, Paola Baiardi2, Bruno Balbi1.
1Divisione di Pneumologia Riabilitativa, IRCCS Fondazione Salvatore Maugeri, Veruno,Novara, Italy; 2Department of Statistics, Consorzio Valutazioni BiologicheFarmacologiche, Pavia, Italy
XLI Congresso Nazionale AIPO – Bologna -2011

Efficacia nel trattamento delle sindromi da ipersecrezione bronchiale mediante tecnica TPEP. Il progetto UNIKO
Autori: Elena Venturelli1, Bruno Balbi2, Francesco d’Abrosca2, Michele Vitacca3, Mara Paneroni3, Guido Vagheggini4, Pierpaolo Cavicchioli4, Michele Zaurino5, Vittoria Galimberti5, Franco Pasqua6, Ida Guidi6, Ernesto crisafulli1, Assunta de Biase1, Nicolino Ambrosino4, Enrico M. Clini1.
1Ospedale Villa Pineta e Università di Modena- Pavullo n/F (MO); Fondazione Maugeri IRCCS-Centro di 2Veruno (NO) e 3Lumezzane (BS), 4 centro di riabilitazione Auxilium Vitae – Volterra (PI); 5Ospedale San giuseppe-Milano; 6Ospedale San Raffaele IRCCS – Velletri (RM). Italy
XLI Congresso Nazionale AIPO – Bologna -2011

UNIKO-TPEP. UNA “SCATOLA MAGICA” PER QUALCHE PAZIENTE CON BPCO
Autori: Rizzonelli Fausto, Foschi Lucia, Boccafoglio Fabio, Sella Dino
UO Pneumologia, Ospedale Santa Chiara – Trento
XLI Congresso Nazionale AIPO – Bologna -2011

Comparison of inhaled dose during nebulization with a new prototype device (UNIKO) and with a classical jet nebulizer.
G.Reychler1,2, L.Pitance2,3, P.Delguste1,2, G.Delval4, S.Quennery5, G.Liistro1,2
1Pneumology Unit, 2Institute of Experimental and Clinical research, Pole Pneumology, ENT and Dermatology, 3Department of Maxillo-Facial Surgery, 5Pharmacy – Cliniques Universitaires Saint-Luc, Université Catholique de Louvain – Brussels
ISAM 2011 Rotterdam

Efficacy of airway clearance therapy with different autonomy degrees in nonCF-BE: Randomized cross-over trial
Beatriz Herrero1,2,3, Eva Polverino1,2,3, Dani Martí Romeu1,2,3, Jordi Vilaró1,2,3,4.1 Respiratory Disease Department, Hospital Clínic, Barcelona, Spain; 2IDIBAPS (Institut d’Investigacions Biomèdiques Agustí Pi Sunyer), University of Barcelona, Barcelona, Spain; 3CIBERES, CIBER de Enfermedades Respiratorias, Mallorca, Spain; 4Facultat de Ciències de la Salut Blanquerna, Universitat Ramon Lull, Barcelona, Spain
ERS 2011 Amsterdam

Airway clearance techniques (ACT): A retrospective study in 188 patients, 96 of which with respiratory failure (RF)
Francesco D’Abrosca1, Barbara Garabelli1, Lorenzo Appendini1, Gloria Savio1 , Agnese Barison1, Nadia Buschini1, Paola Baiardi2, Bruno Balbi1.
1Divisione di Pneumologia Riabilitativa, IRCCS Fondazione Salvatore Maugeri, Veruno, Novara, Italy; 2Department of Statistics, Consorzio Valutazioni Biologiche Farmacologiche, Pavia, Italy.
ERS 2011 Amsterdam

FREE ASPIRE

Treatment of patients with inefficient cough: observational study on the use of the FREE ASPIRE device.
Thesis by Anna Pedroni – Università degli studi di Milano. Faculty of Medicine and Surgery – Degree in Physiotherapy – 2011

The effect of the FREE ASPIRE device (Vaküm technology) on unblocking bronchialobstructions in COPD patients : comparison with protocols in use.
Thesis by Chiara Bani Alunno – Università degli studi dell’Insubria. Degree in Physiotherapy – Varese 2010/2011

Effets de l’aide expiratoire FREE ASPIRE dans la prise en charge kinésithérapique d’un patient atteint de mucoviscidose – Effects of expiratory aid FREE ASPIRE in the physiotherapy treatment of a cystic fibrosis patient.
Thesis of student:: J.FargierHaute – Ecole libre de Bruxelles – Ilya Prigogine anno 2011

UNIKO

Studio pilota di un protocollo riabilitativo respiratorio con sistema temporary Positive Expiratory Pressure in 22 pazienti sottoposti a lobectomia polmonare.
Tesi di Laurea di:  Valentina Bisignano
UNIVERSITA’ DEGLI STUDI DELL’INSUBRIA – Corso di Laurea in Fisioterapia Varese 2010.

Efficacy of temporary positive expiratory pressure to assist patients with chronic hypersecretion. A multicentre randomised trial.
Elena Venturelli1, Ernesto Crisafulli1, Bruno Balbi2, Luca Bianchi3, Guido Vagheggini4, Piergiorgio Schiavoni5, Michele Vitacca3, Michele Zaurino5, Nicolino Ambrosino4, Adrian Kendrick6 and  Enrico M.Clini1 on behalf of the UNIKO study group.
1Ospedale Villa Pineta and University of Modena, Pavullo n/F; Fondazione Maugeri IRCCS, Centers of 2Veruno and 3Lumezzane; 4Auxilium Vitae Rehabilitation Center, Volterra; 5Ospedale San Giuseppe, Milano; 6Bristol Royal Infirmary, Bristol.
Italy and UK.
ERS 2010 Barcellona – Oral presentation

The effects of T-PEP on ventilation lung scan in patient with bronchiectasis: protocol for randomized controlled trial.
Authors: P.Fazzi1,A.D’Abrosca2,R. Cristofani3,S. Derlin1, G. De Cusatis1, S. Antonelli1, FL Dente1, PL Paggiaro1
1Cardio-Thoracic and Vascular Department, University of Pisa, 2Experimental Pathology, Medical Biotechnology, Infection Disease and Epidemiology department, University of Pisa, Pisa Italy

ERS 2010 Barcellona

Effectiveness of the temporary positive expiratory pressure during aerosol therapy in the management of patients with tracheobronchial stent
R. Marchese, G. Paglino, V. Gebbia
Department of Interventional Pulmonology, Department of Medical Oncology, Oncologic Center La Maddalena, Palermo, Italy

ERS 2010 Barcellona

Paziente respiratorio complesso: tecniche di disostruzione bronchiale
Autori: B. Balbi, F. D’Abrosca
Il fisioterapista | Settembre – Ottobre 2010 | fascicolo 5 |

FREE ASPIRE

The rehabilitative treatment by FREE ASPIRE can  reduce pulmonary hypertension in patients with  post-cardiac surgery heart failure. Hemodynamic evaluation  of echocardiographic parameters
M. Solinas*, G. Mengozzi**,  A. Di Vincenzo*, G. Solarino**,  A. Frijia*,. M- Petrilli*.
O.U. of  Cardiovascular and Respiratory Rehabilitation, Don Gnocchi-ONLUS Foundation, Marina di Massa –  Italy ** Cardiovascular Department Hospital University of Pisa
ERS 2010 Barcelona

UNIKO

Positive expiratory pressure techniques in respiratory patients: old evidence and new insights
E. Clini – University of Modena(RE) – Italy
Breathe | December 2009 | Volume 6 | No 2

Valutazioni a breve termine di una pressione positiva temporanea (T-PEP) a scopo disostruente vs pep mask in pazienti affetti da Fibrosi Cistica
Brivio A., Caverni E., Costantini D. –  Paeditric clinic de Marchi, cystic fibrosis centre, Milano
XV Congresso Fibrosi Cistica Italia 2009

Studio preliminare sull’efficacia del sistema T-PEP UNIKO”® rispetto alla PEP Mask nel migliorare i parametri funzionali di pazienti affetti da BPCO di grado severo con ipersecrezione e di pazienti con bronchiectasie.
Authors: A. Frijia1, M. Zingoni1, M. Solinas1, G. Borelli2, R. Albertelli1, M. Petrilli1
1Fondazione Don Gnocchi Marina di Massa (MS), 2Cardio-Thoracic Dept University of Pisa Italy
Rivista Italiana di Fisioterapia e Riabilitazione Respiratoria – Anno VIII Numero 2 Maggio-Agosto 2009

Efficacy of temporary positive expiratory pressure (TPEP) device in chronic hypersecretion. The UNIKO project.
Authors:Ernesto Crisafulli1, Bruno Balbi2, Luca Bianchi3, Guido Vagheggini4, Enrico Guffanti5, Michele Vitacca3, Nicolino Ambrosino4, Enrico M.Clini11Villapineta (MO), 2FSM Veruno (NO), 3FSM Lumezzane (BS), 4Auxilium Vitae Volterra (PI), 5INRCA Casatenovo (LC)
ERCA congress Stresa 2009

Efficacy of the respiratory rehabilitation system “T-PEP UNIKO”® versus pep mask in improving functional parameters of patients with severe COPD and bronchiectasis
Authors: 1A. Frijia, 1M. Zingoni, 1M. Solinas, 2G. Borelli, 1R. Albertelli, 1M. Petrilli. – 1Fondazione Don Gnocchi Marina di Massa (MS), 2Cardio-Thoracic Dept University of Pisa Italy
ERCA congress Stresa 2009

Respiratory physiotherapy in abdominal major surgery. Leading study of a rehabilitative protocol with UNIKOTPEP®
Zeroli Francesca, D’Amanzio Erminia, Boni Luigi. – Università dell’ Insubria Varese Italy
ERCA congress Stresa 2009

Chest physical therapy in chronic bronchitis. The effect of temporary positive expiratory pressure (TPEP) and eltgol. What is the best? The key is patient satisfaction
G. Schiavoni, A. Pediconi, P. D’ Ambrosio,L. Fallarino, M.Iannì, F.Yaine, C. Cigolini, M. Zaurino. – Hospital San Giuseppe Milan, Italy
ERCA congress Stresa 2009

Efficacy of pulmonary rehabilitation programme (PRP) with TPEP® (TEMPORARY POSITIVE EXPIRATORY PRESSURE) about the removal of bronchial secretions, pulmonary function test, dyspnoea and exercise tolerance in COPD patients
Authors: Ferri L, Di Toro S., Dall’Armi V., Cardaci V. – IRCCS San Raffaele la Pisana Rome, Italy
ERCA congress Stresa 2009

Lung ventilation scintigraphy in the assessment of obstructive lung diseases
Authors: P. Fazzi1 R. Albertelli1 M. Grana2 P.L. Paggiaro11Cardio-Thoracic and Vascular Dept and 2General Surgery and Transplantations, University of Pisa, Italy
Breathe | March 2009 | Volume 5 | No 3

FREE ASPIRE

Rehabilitation using FREE-ASPIRE  reduces pulmonary hypertension in cardio-surgery patients with cardiac insufficiency.  Ecocardiographic evaluation of hemodynamic parameters
M. Solinas*, G. Mengozzi**,  A. Di Vincenzo*, G. Solarino*,  A. Frigia*, M. Petrilli*.
* Rehabilitation cardio-respiratory, Foundation don Gnocchi Marina di Massa. **Cardiology university, Dip. Cardiothoracic Pisa
SIC Rome 2009

Preliminary ecocardiographic observations in the reduction of pulmonary hypertension in patients undergoing rehabilitation therapy using acceleration in expiratory air flow (FREE-ASPIR MPR).
M. Solinas*, G. Mengozzi**, G. Borelli**, G. Solarino**, M.Zingoni*, R. Alberelli*, A. Frija*, M. Petrilli** Rehabilitation cardio-respiratory, Foundation don Gnocchi Marina di Massa. **Cardiology university, Dip. Cardiothoracic PisaERCA Stresa 2009

UNIKO

Fisioterapia Respiratoria in chirurgia addominale maggiore. Studio pilota di un protocollo riabilitativo con sistema UNIKO®TPEP
Tesi di Laurea di:  Francesca Zeroli
UNIVERSITA’ DEGLI STUDI DELL’INSUBRIA – Corso di Laurea in Fisioterapia Varese 2008

Efficacia dell’utilizzo dell’apparecchio T-PEP® (Temporary Positive Expiratory Pressure, modello UNIKO®) per la disostruzione bronchiale: proposta di un disegno di studio
Master in fisioterapia e riabilitazione respiratoria di: Antonella Cortelezzi
UNIVERSITA’ DEGLI STUDI DI MILANO – Master 2008

La terapia aerosolica con apparecchio IPPB con TPEP: una prospettiva futura per completare il trattamento della bronchiolite?
Authors:R. Startari, M. Pandolfi, R.M. Porzia, L. Notari, R. Ghilardi, L. Bernardo – Azienda ospedaliera Fatebenefratelli ed Oftalmico – Paediatric department Milano
MINERVA PEDIATRICA Vol. 60 – N. 5 – Pag. 1244 (Ottobre 2008)

Abdominal surgery in COPD: utility of IPPB with temporary expiratory pressure (T-PEP) on distribution of ventilation and gas-exchange.

Authors: P.Fazzi1, R.Albertelli1, M.S.Derlin1, G.Girolami1, M.Grana2, F.Mosca2, C.Giuntini11Cardiothoracic Department, University of Pisa, Pisa, Italy; 2General Surgery and Transplantations, University of Pisa, Pisa, Italy
ERS annual congress Berlin 2008

UNIKO

IPPB with temporary expiratory pressure (T-PEP) in surgical patients with COPD
Authors: P. Fazzi1, G. Girolami2, R. Albertelli1, M. Grana2, F. Mosca2, C. Giuntini11Cardiothoracic Department, University of Pisa Italy. 2General surgery and transplantation, University of Pisa Italy
ERS annual congress Stockholm 2007

Impiego di una pressione positiva temporanea (T-PEP) in pazienti chirurgici affetti da BPCO
Authors: P. Fazzi1,G. Girolami2, R. Albertelli1, M. Grana2, F. Mosca2, C. Giuntini1
affiliations: 1Dipartimento Cardiotoracico, Universita’ degli studi di Pisa – Pisa Italy, 2Chirurgia generale e trapianti, Universita’ degli studi di Pisa – Pisa Italy
7° Congresso Nazionale della Pneumologia SIMeR – Firenze 2006

UNIKO

Valutazioni preliminari sull’impiego di una pressioen positiva temporanea (T-PEP) per l’effettuazione di fisioterapia respiratoria in pazienti affetti da Fibrosi Cistica
Authors: E. Rizza, M. Bernardi*, R. Bini*, E.G. Barlocco* – Centro Regionale di Medicina Nucleare Università Pisa *Servizio per la Fibrosi Cistica – U.O. Pediatria e Neonatologia Ospedale Misericordia Grosseto
XII congresso italiano della Fibrosi Cistica Firenze 2006

UNIKO

Valutazioni preliminari sull’impiego di una pressioen positiva temporanea (T-PEP) per l’effettuazione di fisioterapia respiratoria in pazienti affetti da Fibrosi Cistica
Authors: E. Rizza, M. Bernardi*, R. Bini*, E.G. Barlocco* – Centro Regionale di Medicina Nucleare Università Pisa *Servizio per la Fibrosi Cistica – U.O. Pediatria e Neonatologia Ospedale Misericordia Grosseto
XII congresso italiano della Fibrosi Cistica Firenze 2006